This overview was created under the auspices of KnowledgePoint360 Group, LLC, and was not associated with funding via an educational grant or a promotional interest.
McBeth and colleagues compared the impact of cognitive behavioral therapy (CBT) delivered via phone, exercise, or a combination of the two interventions among subjects with chronic widespread pain.
Subjects (N=442) with chronic widespread pain (as per American College of Rheumatology criteria) were randomized to one of the following interventions over a 6-month study period: CBT via phone, graded exercise, CBT via phone + graded exercise, or treatment as usual.
The study’s primary outcome was change in health status, which was assessed via a seven-point scale (range: “very much worse” to “very much better”; positive outcome defined as “much better” or “very much better”) at baseline, 6 months, and 9 months post-randomization.
Results
|
|
6 months
|
9 months
|
|
Treatment as usual
|
8%
|
8%
|
|
CBT via phone
|
30%
|
33%
|
|
Graded exercise
|
35%
|
24%
|
|
CBT via phone + graded exercise
|
37%
|
37%
|
-
When adjusted for variables including age, baseline predictors of outcome, and sex, active interventions demonstrated improved outcomes vs treatment as usual
|
|
6 months
OR (95% CI)
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9 months
OR (95% CI)
|
|
CBT via phone
|
5.0 (2.0–12.5)
|
5.4 (2.3–12.8)
|
|
Graded exercise
|
6.1 (2.5–15.1)
|
3.6 (1.5–8.5)
|
|
CBT via phone + graded exercise
|
7.1 (2.9–17.2)
|
6.2 (2.7–14.4)
|
OR=odds ratio; CI=confidence interval.
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This overview was created under the auspices of KnowledgePoint360 Group, LLC, and was not associated with funding via an educational grant or a promotional interest.
April 2012